Pain – should it be killed or its source corrected and the cause removed? Which is better solution? Fever – should it be suppressed or tolerated or even moderately promoted? I knew the precise answers for over 30 years from Ayurvedic & Homeopathic studies, but found it very difficult to carry conviction with most of my patients who come to me – totally indoctrinated with widely publicized and generally accepted concepts of modern medicine. I did not have adequate quantum of modern lingo earlier – now I have! Thanks to Jon Barron!
How aspirin works?
Virtually all of aspirin’s benefits stem from its ability to inhibit your body’s production of prostaglandins. Prostaglandins are like hormones in that they act as chemical messengers, but they do not move to other places in the body. They work within the cells where they are made. Their role is to direct responses in the human body. For example, prostaglandins play a role in directing the body’s pain and inflammation response to injury. They help control how fast blood clots in response to a wound, or how readily plaque is formed when there is damage to an arterial wall. They also play a role in directing uterine contractions, not to mention your body’s immune response, and even aspects of metabolism. Aspirin and NSAIDS (non-steroidal anti-inflammatory drugs) such as ibuprofen and Motrin work by decreasing prostaglandin levels. They do this by inhibiting the production of the cyclooxygenase enzymes — both COX-1 and COX-2. The presence of COX-2 is required for the production of prostaglandins. Thus, if you inhibit COX 2, you inhibit the production of prostaglandins.
As it turns out, COX-1 and COX-2 enzymes each serve as a “check and balance” for one another. If you selectively reduce one, you unleash the other. This produces a dangerous imbalance which is what has led to the heart attacks, strokes, blood clots, and other cardiovascular side effects linked to selective COX-2 inhibitor use. But worst of all, the evidence suggests that Merck Pharmaceuticals, the maker of both Vioxx and Celebrex, not only knew of the dangers but failed to warn the public and deliberately falsified data used to validate the drugs…and their safety — with full FDA complicity.